Book Description:
The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator. The design of signalling cascades is explained by describing central signalling pathways: the Ras-regulated MAPK and PI-3 pathways; the Rho/Rac/Cdc 42 pathway controlling chemotaxis and regulating the cytoskeleton; the G protein coupled receptor cascades in response to sensory and hormonal signals; signalling by TGF-ss in morphogenesis; cytokine signalling that controls haemopoiesis. There is also a discussion of the insulin response. As phosphorylation - dephosphorylation is involved in nearly all cellular regulatory processes, Part 1 concludes with a synopsis of its role in signalling. Part 2 describes the implementation of the signalling cascades focusing on the effect on gene transcription. After a brief description of the transcriptional machinery the regulation of transcription by cytokines and growth factors in the control of cell growth and the mechanisms and sites of control are discussed in detail. The regulators discussed include Jun/Fos, NF-AT, SREBPs, and STATs. The next two chapters cover gene regulation by nuclear receptors, including both the steroid hormone receptors and non-steroid nuclear receptors e.g. the retinoic acid receptors RAR and RXR. Part 3 studies the global cellular regulatory programs for the control of cell growth and proliferation. The first chapter concerns the regulation of the cell cycle and the role of the cyclin-dependent kinases, telomerase, Ran, and cell cycle checkpoints. The next topic is the signalling pathways in apoptosis: the TNF-receptor family death receptors, caspases, and the intracellular apoptosis signals and the role of apoptosis in the lifecycle of cells. Part 3 ends with a discussion of the signal pathways involved in the immune response, focusing on the involvement of cell-cell interactions. Part 4 considers loss of regulatory control and its consequences with respect to the molecular basis of cancer. It first describes the cellular regulatory proteins that have oncogenic potential, how they can become oncogenic and cause the transformation of normal cells to cancerous cells. Next is an analysis of the loss of developmental controls, the APC protein, ss-catenin, and the Wnt pathway, that lead to mature terminally differentiated cells reverting to immature embryonic cells. The book ends with a summary of the molecular and cellular causes of cancer and an outlook for novel therapies. Throughout the text, the emphasis is on structure and mechanism and is well illustrated with 200 figures. The Biochemistry of Cell Signalling will be an invaluable companion to all graduate students studying cell signalling.
Product Details
»Book Publisher: Lippincott Williams & Wilkins (01 May, 2005)
»ISBN: 1405104112
»Book author: Vikas Bhushan, Vishal Pall, Tao Le
»Amazon Rating: 4.0
Book Description:
Blackwell Underground Clinical Vignettes: Biochemistry, Fourth Edition is your primary source for clinically relevant, case-based material essential for USMLE Step 1 review. Each Clinical Vignette simulates USMLE format, and includes classic buzzwords in history taking, physical examination, lab, imaging, and pathology. This revised edition contains: / Carefully selected cases templated to fit the way you are tested and taught to think / Valuable links to Step 1 and 2 Atlases for emphasis on photographic case studies / Over 50 new cases compatible with the updated content of USMLE Step 1 Blackwell Underground Clinical Vignettes: Biochemistry, Fourth Edition is perfect for medical students. Physician assistants, nurse practitioners, and related health professionals will also find Underground Clinical Vignettes valuable.
Product Details
»Book Publisher: W. H. Freeman (15 February, 2002)
»ISBN: 0716746840
»Book author: Jeremy M. Berg, John L. Tymoczko, Lubert Stryer
»Amazon Rating: 3.5
Product Details
»Book Publisher: Natl Academy of Science (October, 2003)
»ISBN: 030908881X
»Book author: Leonard A. Cole
»Amazon Rating: 4.5
Book Description:
At 2:00am on October 2, 2001, Robert Stevens entered a hospital emergency room. He was feverish, nauseated, and barely conscious. Notations on his admitting chart indicate that he was “not oriented to person, place, or time.” Perplexed by the sudden and especially severe onset of his symptoms, doctors ran a variety of tests. As armies of bacterial agents attacked and shut down every major organ in Bob Stevens’s system, doctors quickly accumulated and analyzed medical data, fitting the pieces of this complicated puzzle together to arrive at a stunning diagnosis. Bob Stevens had anthrax — and he was soon to become the first official bioterrorism fatality in America.
Book Description:
This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields
Product Details
»Book Publisher: Humana Press (15 March, 2001)
»ISBN: 0896036820
»Book author: Kenneth P. Murphy
»Amazon Rating:
Book Description:
In Protein Structure, Stability, and Folding, Kenneth P. Murphy and a panel of internationally recognized investigators describe some of the newest experimental and theoretical methods for investigating these critical events and processes. Among the techniques discussed are the many methods for calculating many of protein stability and dynamics from knowledge of the structure, and for performing molecular dynamics simulations of protein unfolding. New experimental approaches presented include the use of co-solvents, novel applications of hydrogen exchange techniques, temperature-jump methods for looking at folding events, and new strategies for mutagenesis experiments. Unique in its powerful combination of theory and practice, Protein Structure, Stability, and Folding offers protein and biophysical chemists the means to gain a more comprehensive understanding of some of this complex area by detailing many of the major techniques in use today.
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Publisher: Lippincott Williams & Wilkins
Number Of Pages: 352
Publication Date: 1998-10-01
Sales Rank: 12012
ISBN / ASIN: 0683304917
EAN: 9780683304916
Binding: Paperback
Manufacturer: Lippincott Williams & Wilkins
Studio: Lippincott Williams & Wilkins
The book gives a very clear and concise review of many topics while still hitting on the main points. There are many good diagrams and tables, and the questions at the end of each chapter are very good.
Publisher: World Scientific Publishing Company
Number Of Pages: 396
Publication Date: 2004-02
Sales Rank: 1812695
ISBN / ASIN: 9812384057
EAN: 9789812384058
Binding: Hardcover
Manufacturer: World Scientific Publishing Company
Studio: World Scientific Publishing Company
Book Description:
This important book reviews extensively the preparative chemistry of various nanostructured materials, as well as structural-property correlations for these new materials. Materials of current interest, such as nanocrystals, nanowires, nanotubes, porous materials, and composites, are comprehensively covered
Publisher: Humana Press
Number Of Pages: 600
Publication Date: 2003-05-22
Sales Rank: 1457530
ISBN / ASIN: 1588290689
EAN: 9781588290687
Binding: Hardcover
Manufacturer: Humana Press
The first compilation of classic and emerging laboratory techniques for the study of the biochemistry and cell biology of protein kinase C (PKC). Described in step-by-step detail, these methods can be easily used to explore the structure, function, regulation, subcellular localization, and macromolecular interactions of protein kinase C.. Each protocol is introduced in the context of PKC function and regulation and contains many notes on how best to deal with the problems that may occur. Comprehensive and authoritative, Protein Kinase C Protocols is a timely compilation of biophysical, biochemical, cell biological, and molecular biological approaches that brings protein kinase C research into any laboratory interested in studying it.
5.7 MB PDF, WinRAR archived
Note: this is the GENUNINE MMB volume 233 PKC protocols
Publisher: Springer
Number Of Pages: 302
Publication Date: 2004-08-10
Sales Rank: 4678168
ISBN / ASIN: 030648661X
EAN: 9780306486616
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating:
Total Reviews:
Book Description:
This volume covers some powerful biophysical methods, such as analytical centrifugation, mass spectrometry, fluorescence spectroscopy, electron spin resonance and nuclear magnetic resonance, for the study of complex biological structures, and discusses useful physical concepts as applied to biological and biochemical systems. Case-orientated studies concentrating on particular methodologies are presented and examples are given, addressing some of the most important aspects of structure-function relationship in biological assemblies. Biophysics nowadays collaborates closely with molecular biology and bioinformatics and this is also demonstrated in this book.
The book will be of interest both to experienced researchers wishing to widen their insight into molecular structure and function, and to younger scientists at the doctoral and postdoctoral level interested in the molecular nature of fundamental biological entities and phenomena.
Product Details
pages: 383 pages
Publisher: Humana Press
ISBN: 158829286X
Format: PDF
Summary:
Seasoned practitioners from many leading laboratories describe their best readily reproducible screening strategies for isolating useful clones..
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08-05-2007, 05:30 PM
The Biotechnology of Ethanol: Classical and Future Applications
Book Description
Focusing on the biotechnology of ethanol, this book highlights its industrial relevance as one of the most important products of primary metabolism. The text covers the most advanced developments among classical methods as well as more unconventional techniques, before going on to outline various aspects of new applications and the increasing importance of ethanol as a renewable resource. Topics covered in this unique volume include alternative raw materials, such as municipal waste and waste paper or particular crops, innovative methods of production using genetically engineered microorganisms, and the role of ethanol as both a source of energy and a valuable commodity. The book is a valuable reference in that it combines biotechnological and economic aspects, while also providing an overview of the state of the art in the production and use of ethanol. Throughout, special emphasis has been placed on a balanced presentation between developments in Europe as well as in North and South America. With contributions of T. Senn and H.J. Pieper and of N. Kosaric and F. Vardar-Sukan.
Reviews:
"...a concise overview of the manufacture of ethanol and its many uses..." (SciTech Book News, Vol. 26, No. 2, June 2002)
Worth about a million dollars in feasibility research , September 23, 2004
Reviewer: A. L. Jones (Billings, MT United States)
The book is so lucidly organized and illustrated that a low technology mind like mine easily handled it yet it's a far richer and more sophisticated look at ethanol production options, methods, feedstock economics, output economics, etc. than I've found anywhere. Anyone who wants to do something with ethanol should be forced to buy and devour this book before proceeding further (it'll save them years and millions of dollars in actually getting one done.)
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08-05-2007, 05:36 PM
Encyclopedia of Biological Chemistry, Four-Volume Set, Volume 1-4
Publisher: Academic Press
Number Of Pages: 3000
Publication Date: 2004-10-20
Sales Rank: 1770962
ISBN / ASIN: 0124437109
EAN: 9780124437104
Binding: Hardcover
Manufacturer: Academic Press
Studio: Academic Press
Average Rating:
Total Reviews:
Book Description:
Written for a broad, cross-disciplinary audience, the Encyclopedia of Biological Chemistry addresses the fundamental discipline of biological chemistry underlying virtually all of the life sciences. This compilation of more than 500 different entries encompasses all aspects of biochemistry, as well as the extensions of this subject into the related fields of molecular biology, cell biology, genetics and biophysics. This comprehensive encyclopedia covers all areas of biological chemistry written by more than 500 selected international experts. Articles are generously illustrated including more than 800 images in four-color. Each entry contains a clear, concise review of the topic along with illustrations, a glossary of technical terms and a section for additional reading.
Each entry further contains general background and term definitions as well as a comprehensive review of the current research in the field. Students, science journalists and scientists seeking a concise introduction to specific topics will appreciate the clear, tabular format of each entry.
Also available online via ScienceDirect featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com.
*Four-volume set with topics arranged from A to Z for easy reference
*Seven subject areas covering all areas of biological chemistry
*Over 500 full-color articles of 4-9 pages each
*Over 1300 illustrations throughout with 800 in 4-color and over 200 tables
*Glossary of specialized terms and 'Further Reading' section provided for every article
*Includes entries on the latest research techniques
*Appropriate for students, researchers, and professionals
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Part 1: vol 1 & 2
Part 2: vol 3 & 4
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08-05-2007, 05:39 PM
(Toxicological Chemistry and Biochemistry, Third Edition (Toxicological Chemistry & Biochemistry
Publisher: CRC
Number Of Pages: 425
Publication Date: 2002-09-25
Sales Rank: 1473581
ISBN / ASIN: 1566706181
EAN: 9781566706186
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Average Rating: 5
Total Reviews: 2
Book Description:
Bridging the gap between toxicology and chemistry, this book covers both at a level understandable by a wide spectrum of readers. The third edition of a best-selling resource, it has been thoroughly updated and expanded to reflect recent advances in areas such as the toxic effects and analysis of xenobiotics. A new chapter on the genetic aspects of toxicology discusses how chemical damage to DNA can cause mutations, cancer, and other adverse effects on specific body systems. The author explores the role of genetics in determining individual susceptibilities to various toxicanants. With review questions and references at the end of each chapter, this book is ideal as both a textbook and a reference
Publisher: Elsevier Science
Number Of Pages: 176
Publication Date: 2006-03-07
Sales Rank: 796431
ISBN / ASIN: 1856174662
EAN: 9781856174664
Binding: Hardcover
Manufacturer: Elsevier Science
Studio: Elsevier Science
Average Rating:
Total Reviews:
Book Description:
This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries for the analysis and purification of drugs, small molecules, proteins and DNA.
This book
Provides practical, hands-on advice based on years of experience
Will help ensure optimal design, equipment and separation results for your particular task
Presents system layouts from laboratory to process scale
Will help you to devise or improve record-keeping and documentation systems
Provides practical, hands-on advice based on years of experience
Will help ensure optimal design, equipment and separation results for your particular task
Presents system layouts from laboratory to process scale
Will help you to devise or improve record-keeping and documentation systems
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08-05-2007, 05:48 PM
Protein Analysis and Purification: Benchtop Techniques
Publisher: Birkhäuser Boston
Number Of Pages: 520
Publication Date: 2004-10-21
Sales Rank: 777836
ISBN / ASIN: 0817643400
EAN: 9780817643409
Binding: Hardcover
Manufacturer: Birkhäuser Boston
Studio: Birkhäuser Boston
Average Rating: 5
Total Reviews: 2
Book Description:
This comprehensive, practical, and user-friendly manual is designed to be a practical progression of experimental protocols that an inexperienced investigator may follow when embarking on a biochemical or biotechnology project. It will also appeal to experienced researches and graduate students as a benchtop handbook which, without sacrificing scientific concepts, maintains the spirit of experimentation.
Publisher: Wiley
Number Of Pages: 302
Publication Date: 2006-09-11
Sales Rank: 3761100
ISBN / ASIN: 0470092092
EAN: 9780470092095
Binding: Hardcover
Manufacturer: Wiley
Studio: Wiley
Average Rating:
Total Reviews:
Book Description: )
This title takes an interdisciplinary approach to the central role of solubility in pathological biomineralisation, ranging from traditional thermodynamics and kinetics to unusual concepts such as the PILP process. The scientific background and expertise of the contributors, ranges accordingly from solubility modelling and database development, renal stone and bone implant research, Mössbauer spectroscopy and structural chemistry to biochemistry and crystallisation. The chapters all have a quantitative, physico-chemical component rather than giving purely phenomenological descriptions. The contributors deal with aspects and concepts that have not previously been common in the study of pathological biomineralisation processes.
Publisher: Elsevier Science
Number Of Pages: 900
Publication Date: 2002-12-01
Sales Rank: 770430
ISBN / ASIN: 0444501991
EAN: 9780444501998
Binding: Paperback
Manufacturer: Elsevier Science
Studio: Elsevier Science
Average Rating: 4.5
Total Reviews: 2
Book Description:
The Essence of Chromatography presents a comprehensive survey of modern chromatography and is intended as a suitable text for graduate level courses in the separation sciences and as a self-study guide for professional chromatographers wishing to refresh their background in this rapidly expanding field.
This title is an effective replacement for Chromatography Today, written by the same author with Salwa K. Poole, which is considered to be one of the definitive chromatographic texts of the last decade. Its format is modular, with extensive cross-references to permit rapid location of related material using different separation concepts. Important features are extensive tabulation of essential data for performing separations and an extensive bibliography to the most recent literature.
· Comprehensive and authoritative coverage of chromatographic techniques
· Contains extensive coverage of recent literature on this subject
· Ideal text for graduates and suitable for professional chromatographers
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By
Publisher: Springer
Number Of Pages: 332
Publication Date: 2006-11-09
Sales Rank: 193987
ISBN / ASIN: 0387333347
EAN: 9780387333342
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating: 3
Total Reviews: 3
Book Description: )
X-ray crystallography has been a vital method for studying the structure of proteins and other macromolecules for many years. As the importance of proteins continues to grow in a wide range of research fields from basic biochemistry and biophysics to pharmaceutical development and biotechnology, more and more researchers have found a knowledge of X-ray diffraction to be an indispensable tool. Professor Drenth, recognized internationally for his numerous contributions to crystallographic research, has provided a technically rigorous introduction to the subject. This book provides the theoretical background necessary to understand how the structure of proteins is determined at atomic resolution. It is intended to be an introduction for graduate students, postdoctoral researchers, and established scientists who want to apply protein crystallography in their own endeavors, or need to understand the subject in order to critically evaluate the literature. Principles of Protein X-ray Crystallography is appropriate as a textbook for courses in biochemistry and biophysics, including protein structure and function, structural biology, and macromolecular structure.
ISBN: 0896036820
Author: Kenneth P. Murphy (Editor)
Publisher: Humana Press
Edition: (March 15, 2001)
Hardcover: 248 pages
URL: /http://www.amazon.com/exec/obidos/redirect?tag=songstech-20&path=ASIN%2F0896036820
Summary:
Univ. of Iowa, Iowa City. Offers protein and biophysical chemists a resource for gaining a way to understand and characterize the basis for the stability of the biologically active native states of proteins. Details major innovative techniques in use and emphasizes the theory behind each experimental approach.
Last Edited By: maxxum on Thursday, 21-Dec-06 05:17:52 GMT
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By
Publisher: Springer
Number Of Pages: 312
Publication Date: 2006-06-01
Sales Rank: 2006956
ISBN / ASIN: 1402042191
EAN: 9781402042195
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating:
Total Reviews:
Book Description: )
Bionanotechnology is the key integrative technology of the 21st century and aims to use the knowledge, gathered from the natural construction of cellular systems, for the advancement of science and engineering. Investigating the topology and communication processes of cell parts can lead to invention of novel biological devices with exciting applications. Though microscale to nanoscale research offers an excellent space for the development of futuristic technologies, a number of challenges must be overcome. Due to paucity of a dedicated literature on the protein based nanodevices we bring you this monograph that combines collective research works of scientists probing into this fascinating universe of bionanotechnology. The monograph has been written with an aim of surveying engineering design principles of biomolecular nanodevices, prototype nanodevices based on redox proteins, bacteriorhodopsins and natural fibers, and touching upon the future developments in the field.
Description
This revised edition provides a survey of current biochemistry and molecular biology in the form of a dictionary. It contains short but informative entries arranged under more than 17,000 headwords. It is intended as a handy reference of first resource for those seeking information outside their immediate knowledge area or for those who need to refresh their memory of fundamental knowledge. This revised edition has been fully up-dated in order to include the new information that has been discovered since the original edition was published in 1997
Colloidal Biomolecules, Biomaterials, and Biomedical Applications
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By
Publisher: Marcel Dekker
Number Of Pages: 496
Publication Date: 2003-08-01
Sales Rank: 2815297
ISBN / ASIN: 0824747798
EAN: 9780824747794
Binding: Hardcover
Manufacturer: Marcel Dekker
Studio: Marcel Dekker
Average Rating:
Total Reviews:
Book News Annotation:
Fifteen chapters by researchers from around the world detail an original homogenous assay for biomolecule detection and capture through duplex colloid particles, as well as new methods for using peptides in particle aggulation. The book presents the utilization of colloids in diagnosis and therapy, with recent research results, new methodologies, and several applications. Studies reporting on the interactions (adsorption, desorption, covalent coupling, etc.) between biomolecules (nucelic acids, proteins, antibodies, peptides, viruses, etc.) are also included.
Book Description:
Colloidal Biomolecules, Biomaterials, and Biomedical Applications is an authoritative presentation of established and recent techniques promising to revolutionize the areas of biomedical diagnostics, therapeutics, pharmaceutics, and drug delivery. This exceptional book details an original homogeneous assay for biomolecule detection and capture through duplex colloid particles, as well as new methods for utilizing peptides in particle agglutination. Featuring contributions from over 30 prominent researchers, it investigates physical studies of the agglutination of sensitive latexes, and indicates benefits to drug delivery through supercritical fluid process production of polymer particles.
Number Of Pages: 218
Publication Date: 2006-06-09
Sales Rank: 786741
ISBN / ASIN: 0387330097
EAN: 9780387330099
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating:
Total Reviews:
Book Description: )
Biotechnological Applications of Photosynthetic Proteins: Biochips, Biosensors and Biodevices provides an overview of the recent photosystem II research and the systems available for the bioassay of pollutants using biosensors that are based on the photochemical activity. The data presented in this book serves as a basis for the development of a commercial biosensor for use in rapid pre-screening analyses of photosystem II pollutants, minimising costly and time-consuming laboratory analyses.
Number Of Pages: 308
Publication Date: 2006-10-13
Sales Rank: 1805416
ISBN / ASIN: 0387321217
EAN: 9780387321219
Binding: Paperback
Manufacturer: Springer
Studio: Springer
Average Rating:
Total Reviews:
Book Description: )
In recent years, cytology has played an increasingly important role in the diagnosis of disease, particularly those of neoplastic origin. It is not unusual for cytologic specimens to be the only diagnostic samples available from patients with cancer. Many ancillary tests traditionally performed on histologic material are now being performed on cytologic specimens. One such technique, immunocytochemistry (ICC), has already proved to be important in diagnostic tumor pathology.
This atlas examines the value of ICC as well as its limitations in contemporary cytology. Methods have been refined and high-quality reagents are now available. As a result, technical problems no longer present a major concern in this field. This volume will briefly address the technical aspects of ICC by providing practical advice for the users and analytical aspects of ICC, including correct selection of markers for specific differential diagnoses and incorporation of results in final cytologic interpretation; illustrate the utilization of ICC in the resolution of some common diagnostic problems in fine needle aspiration and body cavity fluid cytology. ICC of undifferentiated malignant neoplasms, carcinomas of unknown origin, and most importantly its utilization in specific differential diagnoses that are based on cytomorpholoy and patient’s clinical history is also discussed. This practical handbook will allow for quick reference in the selection and interpretation of markers in specific differential diagnostic in the daily practice of diagnostic cytology.
Publisher: Mosby
Number Of Pages: 270
Publication Date: 2003-03-01
Sales Rank: 428919
ISBN / ASIN: 0323008356
EAN: 9780323008358
Binding: Paperback
Manufacturer: Mosby
Studio: Mosby
Average Rating: 4.5
Total Reviews: 2
Book Description:
This text offers a comprehensive yet concise review of biochemistry while discussing all of the relevant clinical information. The review chapters in the first section of the text are in a user-friendly outline format with high-yield information located in margin notes and clinical topics discussed within the outline and in clinical boxes. The second section of the book contains two 50-questions exams in USMLE format. A CD-ROM that accompanies the book contains a full-color art program, 500 board-style questions and answers with rationales for correct answers as well as all incorrect choices, and a quizzing function that gives scores at the end of the exams.
Product Details
»Book Publisher: Oxford University Press, USA (07 August, 2006)
»ISBN: 019517688X
»Book author: Robert H. Glew, Miriam D. Rosenthal
»Amazon Rating:
Book Description:
This text uses a case-study approach to present core principles of biochemistry and molecular biology in the context of human disease. The thirty-three cases have been carefully chosen to cover key concepts and common diseases. Each chapter provides a specific patient report that includes relevant history, pertinent clinical laboratory data, physical findings, and subsequent diagnosis. This is followed by a comprehensive discussion of normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. In this third edition of the book, a new co-editor has aided in the substantially revised and more targeted selection of cases. The whole volume is now clearly focused on intermediary metabolism and other topics central to biochemistry. There are new chapters on topics such as collagen structure, mitochondrial metabolism, and hyperhomocysteinemia and vascular disease. There is also more coverage of nutritional biochemistry, including new chapters on protein-calorie malnutrition, obesity, vitamin A deficiency, and iron metabolism. The best cases were retained from the previous edition, and have been completely rewritten and updated to include recent advances in diagnostic biochemistry and the status of current therapies. Although the first edition was intended primarily for medical students, through the years the book has proven useful for a wide variety of students interested in the health science professions.
Publisher: CRC
Number Of Pages: 427
Publication Date: 2006-08-15
Sales Rank: 1925198
ISBN / ASIN: 0849372291
EAN: 9780849372292
Binding: Hardcover
Book Description:
Human Developmental Toxicants offers up-to-date and concise information on the chemical structures, properties, and biological activities for 50 known agents that adversely affect prenatal and postnatal human development. Focusing on one compound per chapter, the book also includes associated biological data from animals for each agent. An accompanying CD summarizes all of the data discussed in the text within an electronic database. The CD also contains three-dimensional structure representations and 49 calculated physicochemical and topological parameters of each toxicant, useful for building structure activity relationship (SAR) models linking the chemical properties with observed human developmental toxicity.
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04-06-2007, 12:11 PM
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ProfessorBassam
04-06-2007, 10:02 PM
Thanks really for the effort Doctor Mona but......rapidshare.... makes me sad :cry:
ProfessorBassam
04-06-2007, 10:03 PM
Thanks really for the effort Doctor Mona but......rapidshare.... makes me sad :cry:
By N.V. Bhagavan
Publisher: Academic Press
Number Of Pages: 1060
Publication Date: 2001-07
Sales Rank: 1016004
ISBN / ASIN: 0120954400
EAN: 9780120954407
Binding: Hardcover
Book Description:
Thoroughly updated and in a new two-color format, this well- respected text presents the fundamentals of biochemistry and related topics to students pursuing a one- or two-semester course in pre-med biochemistry or medical programs. The second edition is equally applicable to other health-related fields such as clinical chemistry, medical technology or pharmacology. Medical Biochemistry, Fourth Edition, focuses on the foundations and clinically relevant applications of normal human biochemistry and pathology. Abundantly illustrated with four-color plates.
Revised chapters on molecular biology reflect the latest research in the field
Two color throughout with four color plates
Reference quality appendices include practical information on clinical lab parameters used to diagnose a range of diseases
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24-06-2007, 01:03 AM
Chromatin: Structure and Function
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Publisher: Academic Press
Number Of Pages: 447
Publication Date: 1998-01-15
Sales Rank: 1368317
ISBN / ASIN: 0127619151
EAN: 9780127619156
Binding: Paperback
Book Description:
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active involvement in the processes of DNA transcription, replication and repair. This book consistently interrelates the structure of eukaryotic DNA with the nuclear processes it undergoes, and will be essential reading for students and molecular biologists who want to really understand how DNA works.
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52.45 + 52.28 MB MultiVolume RAR'd PDF
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*
* Written in a clear and concise fashion
* Includes 60 new illustrations
* Extensively rewritten
* Brings the reader up-to-date with the remarkable progress in chromatin research over the past three years.
Publisher: Blackwell Publishing Limited
Number Of Pages: 336
Publication Date: 2002-05-01
Sales Rank: 883622
ISBN / ASIN: 0632054093
EAN: 9780632054091
Binding: Paperback
Book Description:
Lipids are essential components of every living cell and a study of them is important for all students of biochemistry, nutrition, food science and medicine. This fourth edition has been completely rewritten and restructured to reflect recent advances and to highlight lipid biochemistry and nutrition, health and disease in Man, focusing on the functions of lipids rather than their chemical structure. A broad range of material is presented in a well-illustrated, extensively cross-referenced and accessible format.
By
Publisher: Springer
Number Of Pages: 356
Publication Date: 2002-05-31
Sales Rank: 2474276
ISBN / ASIN: 0306467828
EAN: 9780306467820
Binding: Hardcover
Book Description:
The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. It is now well recognised that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The molecular mechanisms of apoptosis are presently unknown and the subject of focused research effort. It is clear that cell membrane structure and properties play an early part in the induction process. There is increasing evidence that the arrangement of polar lipids in the membrane lipid matrix is an important factor coupled with the homeostatic mechanisms responsible for preserving membrane lipid composition and asymmetry. Changes in membrane permeability are also likely to be involved, possibly as a direct consequence of disturbances in the lipid bilayer matrix.
The purpose of this volume is to examine the involvement of membrane lipids in early events of apoptosis. In particular, the role of phospholipids in mitochondrial permeability, membrane lipid asymmetry, and sphingolipid and phospholipid signalling processes in early apoptotic events are reviewed by current researchers in these fields.
By
Publisher: CRC
Number Of Pages: 232
Publication Date: 2006-02-22
Sales Rank: 1058083
ISBN / ASIN: 0849341809
EAN: 9780849341809
Binding: Hardcover
Book Description:
Phytochemicals: Nutrient-Gene Interactions analyzes the mechanisms of action and impact of phytochemical-gene interactions on health, aging, and disease. The book covers experimental methodologies for identifying significant interactions between diet, genetic variants, and different markers of cardiovascular disease, inflammation, and obesity. It explores the role of resveratrol in cardiovascular health; the preventative mechanisms of whole grains and omega-3 fatty acids; epidemiological research on plant-based foods; the non-antioxidant cellular properties of vitamin E; and controlled clinical trials. The book illustrates the growing role of nutrigenomics in the responsible development of safe and effective phytochemical products within the food, pharmaceutical, and supplement industries.
Publisher: Wiley-Interscience
Number Of Pages: 346
Publication Date: 2006-10-20
Sales Rank: 2087050
ISBN / ASIN: 0471770019
EAN: 9780471770015
Binding: Hardcover
Book Description:
Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some forms of cancer. This book provides a thorough introduction to GSK-3, presents up-to-date information, and mentions the birth of several chemical families of GSK-3 inhibitors with varying selectivity. It’s a great reference for researchers in drug design and development.
By Andrew Pengelly
Publisher: Sunflower Herbals
Number Of Pages: 109
Publication Date: 1996-09
Sales Rank: 3344654
ISBN / ASIN: 0646315951
EAN: 9780646315959
Publisher: Mosby
Number Of Pages: 384
Publication Date: 2004-05-29
Sales Rank: 542833
ISBN / ASIN: 0723433283
EAN: 9780723433286
Book Description:
The new edition of this extremely successful text explores the clinical application of biochemistry. It explains what happens to the body's chemistry when affected by disease...which laboratory tests are used in various clinical situations...and how to interpret the results. Over 100 actual patient case histories demonstrate how clinical chemistry relates to the practice of medicine. More than 100 crisp line drawingsrendered in full color for the first time in this 5th Editionmake concepts easy to understand. And, self-assessment exercises based on clinical vignettes enable readers to check their comprehension of the material.
By Wendy L. Arneson, Jean M. Brickell,
Publisher: F. A. Davis Company
Number Of Pages: 582
Publication Date: 2007-01-30
Sales Rank: 468923
ISBN / ASIN: 0803614985
EAN: 9780803614987
By Wilfred Vermerris, Ralph Nicholson,
Publisher: Springer
Number Of Pages: 276
Publication Date: 2007-04-04
Sales Rank: 2096047
ISBN / ASIN: 1402051638
EAN: 9781402051630
Binding: Hardcover
Book Description:
How does the consumption of red wine reduce heart disease? How does a plant battle an invading fungus using physical and chemical defense mechanisms? How are tannins used in leather production synthesized?
These are just a few examples that illustrate the chemical diversity and use of phenolic compounds, the topic of ‘Phenolic Compound Biochemistry’.
This book is written for researchers, instructors, advanced undergraduate students and beginning graduate students in the life sciences who wish to become more familiar with these and many other intriguing aspects of phenolic compounds. Topics covered include nomenclature, chemical properties, biosynthesis, including an up-to-date overview of the genetics controlling phenolic metabolism, isolation and characterization of phenolic compounds, phenolics used in plant defense, and the impact of phenolics on human health. The book is written in an accessible style, and assumes only basic knowledge of organic chemistry, biochemistry and cell physiology. More than 300 chemical structures and reaction schemes illustrate the text.
Wilfred Vermerris is Associate Professor of Agronomy at the University of Florida Genetics Institute in Gainesville, FL. His research focuses on the genetic control of phenolic compounds that impact agro-industrial processing of crop plants.
Ralph Nicholson is Professor of Botany and Plant Pathology at Purdue University in West Lafayette, IN. He is an expert on phenolic compounds involved in the plant’s defense against pathogenic fungi and bacteria.
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Principles of Medical Biochemistry:
by Gerhard Meisenberg, William H. Simmons
Publisher: Elsevier Health Sciences
Pub. Date: February 2007
ISBN-13: 9780323029421
Sales Rank: 29,168
696pp
Edition Number: 2
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Handbook on Metalloproteins
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By
Publisher: CRC
Number Of Pages: 1108
Publication Date: 2001-06-29
Sales Rank: 2332231
ISBN / ASIN: 0824705203
EAN: 9780824705206
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Average Rating: 0
Total Reviews: 0
Book Description:
This Handbook on Metalloproteins focuses on the available structural information of proteins and their metal ion coordination spheres. It centers on the metal ions indispensable for life but also considers metal ions used as substitution probes in studies of metalloproteins. Emphasizing the structure-function relationship, the book covers the common and distinct characterstics of metallo- enzymes, proteins, and amino acids bonded to copper, zinc, iron, and more.
Rapid Review Biochemistry: With STUDENT CONSULT Online Access (Rapid Review)
By John W. Pelley, Edward F. Goljan
Publisher: Mosby
Number Of Pages: 320
Publication Date: 2006-11-15
ISBN-10 / ASIN: 0323044379
ISBN-13 / EAN: 9780323044370
Binding: Paperback
Book Description:
Get the most from your study time...and experience a realistic USMLE simulation! These new additions to the Rapid Review Serieshighly rated in the First Aid rankingsmake it easy for you to master all of the basic science material covered on the USMLE Step 1 Exam.
Product Details
»Book Publisher: W. H. Freeman (19 May, 2006)
»ISBN: 0716787245
»Book author: Jeremy M. Berg, John L. Tymoczko, Lubert Stryer
»Amazon Rating: 3.5
Publisher: Mosby
Number Of Pages: 696
Publication Date: 2004-12-17
ISBN-10 / ASIN: 0723433410
ISBN-13 / EAN: 9780723433415
Binding: Paperback
Book Description:
The New Edition of this well-regarded textbook combines basic science and clinical medicine in a concise, easy-to-read format. Fully revised and updated, it reflects the latest information on genetic and molecular biology and integrates even more clinical medicine into the text. At the same time, it retains the dynamic, full-color design that made the first edition such a successcomplete with case histories, advanced concept boxes, and color illustrations that clarify complex biochemical concepts. New summary boxes and an expanded self-assessment section make the text even more useful for review and study.
The smart way to study!
Elsevier titles STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.
Publisher: Elsevier Science
Number Of Pages: 404
Publication Date: 2006-06-26
ISBN-10 / ASIN: 0444517375
ISBN-13 / EAN: 9780444517371
Binding: Hardcover
Book Description:
The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biotechnology industry as escalating R&D costs are not being matched by increased output. Few observers doubt that selecting the right targets, ie those which are critical to disease pathology and are druggable, is the best starting point for improved productivity.
The seven chapters of this volume describe recent progress towards drugs acting at a range of druggable targets. One chapter addresses kinases, one covers an ion channel, two proteases are featured and three of the chapters cover G-protein coupled receptors, which has historically perhaps been the most fruitful area for medicinal chemists.
*Presents the latest research in the field of drug discovery
*Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry
*Available as an online resource via ScienceDirect
Publisher: Wiley-Interscience
Number Of Pages: 528
Publication Date: 2007-10-05
ISBN-10 / ASIN: 0471761133
ISBN-13 / EAN: 9780471761136
Binding: Paperback
Book Description:
An updated, practical guide to bioinorganic chemistry
Bioinorganic Chemistry: A Short Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. Rather than striving to provide a broad overview of the whole, rapidly expanding field, this resource provides essential background material, followed by detailed information on selected topics. The goal is to give readers the background, tools, and skills to research and study bioinorganic topics of special interest to them. This extensively updated premier reference and text:
*
Presents review chapters on the essentials of inorganic chemistry and biochemistry
*
Includes up-to-date information on instrumental and analytical techniques and computer-aided modeling and visualization programs
*
Familiarizes readers with the primary literature sources and online resources
*
Includes detailed coverage of Group 1 and 2 metal ions, concentrating on biological molecules that feature sodium, potassium, magnesium, and calcium ions
*
Describes proteins and enzymes with iron-containing porphyrin ligand systems-myoglobin, hemoglobin, and the ubiquitous cytochrome metalloenzymes-and the non-heme, iron-containing proteins aconitase and methane monooxygenase
Appropriate for one-semester bioinorganic chemistry courses for chemistry, biochemistry, and biology majors, this text is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers who need a general introduction to bioinorganic chemistry, as well as chemists who want an accessible desk reference.
Download Description:
Bioinorganic chemical knowledge grows more interesting and more complex with each passing year. As more details about the usage and utility of metals in biological species and more mechanistic and structural information about bioinorganic molecules becomes available, scientists and students continue to turn their attention to this blossoming discipline. Rosette Roat-Malone's Bioinorganic Chemistry: A Short Course provides an accessible survey of bioinorganic chemistry for advanced undergraduate and graduate students. Comprehensive coverage of several topics offers insight into the increasingly diverse bioinorganic area. Roat-Malone's text concentrates on bioinorganic chemistry's two major focuses: naturally occurring inorganic elements and their behavior in biological systems, and the introduction of inorganic elements into biological systems, often as medicines.
The book begins with two review chapters, Inorganic Chemistry Essentials and Biochemistry Fundamentals. Chapter 3, Instrumental and Computer-Based Methods, provides an introduction to some important instrumental techniques, including basic information about computer hardware and software.
Chapters on specific topics include:
Iron Containing Oxygen Carriers and Their Synthetic Models
Copper Enzymes
The Enzyme Nitrogenase
Metals in Medicine
The author also encourages instructors and students to pursue their own independent investigations in bioinorganic topics, providing a helpful, detailed list of suggestions. With a host of current bibliographic references, Bioinorganic Chemistry: A Short Course proves the premier text in its field.
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By Frank Mustoe, Michael Jansen, Ted Doram, John Ivanco, Christina Clancy, Anita Ghazariansteja,
Publisher: McGraw-Hill Ryerson School
Number Of Pages: 708
Publication Date: 2001-05-22
Sales Rank: 70946
ISBN / ASIN: 0070886814
EAN: 9780070886810
Binding: Hardcover
Manufacturer: McGraw-Hill Ryerson School
Studio: McGraw-Hill Ryerson School
McGraw-Hill Ryerson Chemistry 11 is a dynamic new program researched and written for the Ontario Chemistry, Grade 11 University Preparation course. This highly visual resource will provide excellent concept development and numerous new hands-on investigations to allow students to explore how chemistry is used in the products and processes that affect our lives and the environment.
Features:
- An entirely new resource for grade 11 Chemistry, written by an experienced team of excellent chemistry educators
- Excellent, new hands-on investigations, plus less time-consuming Express labs to actively involve students as they explore chemistry concepts and theories
- A problem solving model that will stimulate students to think through the concepts and not just "plug numbers into formulas"
- A wide variety of sample problems and practice problems that not only help students to learn the principles, but to see how chemistry problems relate to other sciences and to everyday experience
- Visually attractive four-colour textbook, with easy to follow illustrations, that will appeal to students and help clarify the explanation of concepts
- Available in French from Cheneliere/McGraw-Hill to allow bilingual and French Immersion schools to use the same resource
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25-11-2007, 02:08 AM
Chemistry 12
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By Frank Mustoe, Michael Jansen, Michael J. Webb, Christy Hayhoe, Andrew Cherkas, Jim Gaylor, Christa Bedry, Jonathan Bocknek,
Publisher: McGraw-Hill Ryerson School
Number Of Pages: 676
Publication Date: 2002-08-21
Sales Rank: 349939
ISBN / ASIN: 0070916438
EAN: 9780070916432
Binding: Hardcover
Manufacturer: McGraw-Hill Ryerson School
McGraw-Hill Ryerson Chemistry 12 is a new resource written specifically for the Ontario Chemistry, Grade 12 University Preparation course. The student text provides clear, well developed explanations, effective visual support, and a variety of practice problems and activities designed to inspire a sense of competence within students on the threshold of university. The text enlivens the study of chemistry, by showcasing intriguing chemical technologies, careers, profiles of Canadian scientists, and STSE connections.
FEATURES. - A new program that corresponds 100% to the new Chemistry Grade 12 (SCH4U) curriculum.
- Developed by a team of highly talented authors and consultants with many years of teaching experience.
- Accurate, relevant, and up-to-date; content thoroughly reviewed by leading academics as well as pedagogical reviewers.
- Easy-to-navigate, student-friendly text design that features a minimum of distracting elements.
- "Prerequisite Concepts and Skills" listed in each chapter opener alert students to what they need to know before they begin the chapter.
- Specific Expectations are clearly posted at the beginning of each section within a chapter.
- A brief review of key concepts and skills learned in Grade 11 Chemistry eases students into the new Grade 12 material. - Many opportunities for problem solving based on a carefully developed, student-friendly problem-solving model and numerous practice problems. - Appropriate balance of ExpressLabs, ThoughtLabs, Investigations, and Design-Your-Own Labs.
- All labs have been carefully checked by an experienced STAO Safety Committee reviewer.
- An abundance of well-crafted review questions for each section, chapter, and unit; all questions are coded to the Achievement Chart categories.
- Concept Checks, Problem Tips, and Concept Organizers reinforce student comprehension.
- All numerical answers to practice problems and review questions are provided in the student text. - Appendices and data tables at the back of the student text provide quick reference, skill reinforcement, and supplementary practice problemsAdditional electronic support to assist implementation: - a CD-ROM features an interactive student e-book, enhanced by animations, simulations, video clips, and original probeware activities - a web site.
- [www.mcgrawhill.ca/links/chemistry12] supports research, projects, and enrichment opportunities- supplementary CD-ROMs feature blackline masters, labs, and problems in modifiable format, as well as fully worked solutions to all problems in the student text
Studio: McGraw-Hill Ryerson
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25-11-2007, 03:42 PM
Biomedical EPR - Part A: Free Radicals, Metals, Medicine and Physiology
Publisher: Springer
Number Of Pages: 522
Publication Date: 2004-08-19
Sales Rank: 2308823
ISBN / ASIN: 0306485060
EAN: 9780306485060
Binding: Hardcover
Manufacturer: Springer
Book Description: )
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features:
Free Radicals in Medicine
Radicals in vivo and in Model Systems, and their Study by Spin Trapping
In vivo EPR, including Oximetry and Imaging
Time Domain EPR at Radio Frequencies
EPR of Copper Complexes: Motion and Frequency Dependence
Time Domain EPR and Electron Spin Echo Envelope Modulation
Advanced Free Radical Reactions for Organic Synthesis
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By
Publisher: Elsevier Science
Number Of Pages: 270
Publication Date: 2004-01-14
Sales Rank: 2766758
ISBN / ASIN: 0080443745
EAN: 9780080443744
Binding: Hardcover
Book Description:
Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists.
- Introduces and reviews the use of radicals to perform synthetic transformations.
- Practical details are provided for the most important methods.
- Numerous references to the original literature.
By Zory Vlad Todres
Publisher: CRC
Number Of Pages: 464
Publication Date: 2002-09-10
Sales Rank: 3057766
ISBN / ASIN: 0824708105
EAN: 9780824708108
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Book Description:
Examining the formation, transformation, and application of ion radicals in typical conditions of organic synthesis, Organic Ion Radicals: Chemistry and Applications explains the reactions and principles of ion radical chemistry. The author addresses methods of determining ion- radical mechanisms and controlling ion radical reactions, issues relating to ecology and biology, and inorganic participants in ion radical organic reactions. Applications discussed include the roles of ion radicals in biological systems and their uses in optoelectronics, organic metals, and the manufacture of paper.
Electron Spin Resonance Spectroscopy for Organic Radicals
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Synopsis
Gerson (chemistry, University of Basel) and Huber, a chemistry researcher in the private sector, introduce theory and techniques of electron spin resonance (ESR) spectroscopy to users of the technique in both research and industry. Instead of using complex mathematical derivations, the authors present a readily understandable approach to the field by interpreting sample spectra and classifying experimental data. Chapters cover physical fundamentals of ESR, paramagnetic organic species and their generation, electron-nuclear magnetic interaction, spin density and polarization, multiresonance, and taking and analyzing ESR spectra, organic radicals, conjugated hydrocarbon radicals, biradicals, and triplet-state molecules.
Table of Contents
Preface
Abbreviations and Symbols
A: General Part 1
1 Physical Fundamentals of Electron Spin Resonance 3
2 Paramagnetic Organic Species and Their Generation 10
3 Electron-Nuclear Magnetic Interaction 37
4 Spin Density, Spin Population, Spin Polarization, and Spin Delocalization 49
5 Multiresonance 83
6 Taking and Analyzing ESR Spectra 97
B: Special Part 167
7 Organic Radicals Centered on One, Two, or Three Atoms 169
8 Conjugated Hydrocarbon Radicals 210
9 Conjugated Radicals with Heteroatoms 290
10 Saturated Hydrocarbon Radicals 375
11 Biradicals and Triplet-state Molecules 386
App. A.1 Nitroxyls as Spin Labels and Spin Adducts 405
App. A.2 Hyperfine Splitting by Alkali-Metal Nuclei in Counterions of Radical Anions 409
References 415
Index 447
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25-11-2007, 03:51 PM
Free-Radical-Induced DNA Damage and Its Repair: A Chemical Perspective
By
Publisher: Springer
Number Of Pages: 510
Publication Date: 2006-01-09
Sales Rank: 669784
ISBN / ASIN: 3540261206
EAN: 9783540261209
Binding: Hardcover
Book Description: )
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.
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Topics in current chemistry, 108, Radicals in Biochemistry
By: D. E. Edmondson
ISBN-10: 0387118462 ISBN-13: 9780387118468
Publisher: Springer-Verlag - 1982-12
Table of Contents:
Recent Development with Copper Proteins
by Rene A. Lontie, Dominigue R. Groeseneken
at Laboratorium voor Biochemie, Katholieke Universiteit te Leuven, B-3000 Louvain, Belgium
The Metabolism of Superoxide Anion and its Progeny in Blood Cells
by Robert E. Lynch
at Univercity of Utah College of Medicine, Salt Lake City, Utah 84132*, USA
The Flavin Redox-System and Its Biological Function
by Franz Muller
at Department of Biochemistry, Agricultural University, De Dreijen 11, NL-6703 BC Wageningen, The Netherlands
Semiquinone Formation in Flavo- and Metalloflavoproteins
By Dale E. Edmonson (1) and Gordon Tollin (2)
at (1)--> Department of Biochemistry, Emory University, School of Medicine, Atlanta, Georgia 30322
and (2)--> Department of Biochemistry, University of Arizona, Tucson, Arizona 85721, USA
Format: PDF
Archive: RAR
Size: 10.6 Mb
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25-11-2007, 03:57 PM
Radicals for Life: the various forms of nitric oxide
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By
Publisher: Elsevier Science
Number Of Pages: 442
Publication Date: 2007-05-07
Sales Rank:
ISBN / ASIN: 0444522360
EAN: 9780444522368
Binding: Hardcover
Book Description:
Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans.
Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers.
Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, ***ual dysfunction, and renal insufficiency to stroke and ischemia are also included.
* First monograph to consider and provide an overview of endogenous nitrosocompounds and nitrosyl-iron complexes
* Extensive bibliographic references, written by specialists of human physiology
* Providing high scientific quality with a focus on implications for human diseases
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Methods in Enzymology Vol. 233. Oxygen Radicals in Biological Systems Part C
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By: John N. Abelson(Editor) Melvin I. Simon(Editor) Helmut Sies(Editor)
ISBN: 012182134X
Since biological tissues are unstable in an oxygen atmosphere, a great deal of effort is expended by organisms to metabolically limit or repair oxidative tissue damage. This volume of Methods in Enzymology and its companion Volume 234 present methods developed to investigate the roles of oxygen radicals and antioxidants in disease.
Key Features
* Generation, detection, and characterization of oxygen radicals, chemistry, biochemistry, and intermediate states of reductio* Isolation, characterization, and assay of enzymes or substrates involved in formation or removal of oxygen radical
* Methods for assessing molecular, cell, and tissue damage; assays and repair of oxidative damage
This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist.
The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.
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By
Publisher: Greenwood Press
Number Of Pages: 392
Publication Date: 2003-06-30
Sales Rank: 1230542
ISBN / ASIN: 0313316643
EAN: 9780313316647
Binding: Hardcover
Book Description:
Written for students beginning a formal study of chemistry, this volume encompasses many different topics in and approaches to introductory chemistry. Chapters are devoted to topics such as the atom, elements and the periodic table, bonding, equilibrium and kinetics, solutions, acids and bases, and chemical reactions. Several chapters discuss broad areas of chemistry including organic chemistry, biochemistry, environmental chemistry, and industrial chemistry. Illustrations and diagrams help the student understand chemical structures and reactions, and numerous tables present a wealth of reference information. The historical developments of chemical concepts are traced, and biographical information is provided on key individuals responsible for the development of modern chemistry. Appendices include an extensive bibliography, a glossary of over 400 chemical terms, an overview of Nobel laureates in chemistry, and an element reference table. This book will be of use not only to students, but also to anyone seeking an overview of the field. Teachers of all grades can use Basics of Chemistry as a practical general reference.
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By Anthony Wood
Publisher: Academic Press
Number Of Pages: 556
Publication Date: 2006-12-08
ISBN-10 / ASIN: 0120405415
ISBN-13 / EAN: 9780120405411
Binding: Paperback
Book Description:
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.
* Critical reviews of the previous year's literature in many topics of inteest to medicinal chemists
* Highlights major developments in medicinal chemistry
* Includes a comprehensive set of cumulative indices to easily locate topics in all published volumes
Publisher: Wiley
Number Of Pages: 270
Publication Date: 2005-06-17
ISBN-10 / ASIN: 0470092882
ISBN-13 / EAN: 9780470092880
Binding: Hardcover
Book Description:
Chemistry: An Introduction for Medical and Health Sciences provides students and practitioners with a clear, readable introduction to the chemical terms and concepts that are relevant to their study and practice. Assuming little prior knowledge of the subject the book describes and explains the chemistry underlying many of the most commonly prescribed drugs and medicines. It also includes information on chemical aspects of digestion and nutrition, oxidation, radioactivity and an overview of how chemicals fight disease.
Excellent pedagogy including learning objectives, diagnostic tests and questions in each chapter and a comprehensive glossary
Experienced author team with many years experience of teaching chemistry to non-chemists
Download Description:
Chemistry: An Introduction for Medical and Health Sciences provides students and practitioners with a clear, readable introduction to the chemical terms and concepts that are relevant to their study and practice. Assuming little prior knowledge of the subject the book describes and explains the chemistry underlying many of the most commonly prescribed drugs and medicines. It also includes information on chemical aspects of digestion and nutrition, oxidation, radioactivity and an overview of how chemicals fight disease. Excellent pedagogy including learning objectives, diagnostic tests and questions in each chapter and a comprehensive glossary Experienced author team with many years experience of teaching chemistry to non-chemists
Publisher: Wiley
Number Of Pages: 600
Publication Date: 2007-05-25
Sales Rank: 509973
ISBN / ASIN: 0470859032
EAN: 9780470859032
Binding: Paperback
Book Description:
Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail.
Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques
Maintains a careful balance between depth and breadth of coverage
Includes examples, problems and their solutions
Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice.
The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy.
A comprehensive, practical account of the key concepts involved in synthesising compounds
Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations
Focuses on reactions that really work rather than those with limited application
Contains extensive, up-to-date references in each chapter
Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
NMR - From Spectra to Structures: An Experimental Approach by Terence N. Mitchell, Burkhard Costisella
Springer; 2nd rev.and exp.ed. edition (September 10, 2007) | ISBN:3540721959 | PDF | 208 pages | 3.5 Mb
Nuclear magnetic resonance spectroscopy is one of the most powerful analytical methods. This practice-oriented textbook aims at teaching how NMR experiments should be used to make structural asssignments. The book is intended as a practical guide for students and laboratory personnel, so that the emphasis is on practical rather than on theoretical aspects, which are treated only to the extent necessary to understand the experiments and to interpret the results.
The second edition has been expanded to include several other heteronuclei (15N, 19F, 29Si, 77Se, 113Cd, 117Sn/119Sn, 195Pt, 207Pb) and a new chapter on solid state NMR. The problems section has been enlarged and now includes 50 problems. These are of different degrees of complexity and in all cases include two-dimensional (2D) methods as well as standard proton and carbon 1D spectra.
A New Unifying Biparametric Nomenclature that Spans all of Chemistry
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A New Unifying Biparametric Nomenclature that Spans all of Chemistry
Elsevier Science | 0444516859 | Edition - 2004-05-20 | PDF | 324 pages| 9.79 MB | Rapidshare & Megaupload
As a byproduct of historical development, there are different, unrelated systems of nomenclature for "inorganic chemistry", "organic chemistry", "polymer chemistry", "natural products chemistry", etc. With each new discovery in the laboratory, as well as each new theoretical proposal for a chemical, the lines that traditionally have separated these "distinct" subsets of matter continually grow more blurred. This lack of uniformity in characterizing and naming chemicals increases the communication difficulties between differently trained chemists, as well as other scientists, and greatly impedes progress. With the set of known chemicals numbering over 42,000,000 (in Chemical Abstracts' data base) and continually growing (about 2,000 new additions every day), the desirability for a unified system for naming all chemicals simultaneously grows. Moreover, in order to meet the requirements of disparate groups of scientists, and of society in general, the name assigned to a given chemical should, not only uniquely describe that substance, but also should be a part of a readily recognizable order for the entire field. For these purposes, a topology-based "bi-parametric" system of nomenclature is herein proposed.
- In this book, a new nomenclature system is proposed
- The new nomenclature is applicable to a three dimensional world, and is internally consistent
- This nomenclature unifies ALL branches of chemistry, removing the need for various presently existing sets of rules
By Moses Attrep, Bernd Kahn
Publisher: Springer
Number Of Pages: 168
Publication Date: 2007-11-09
ISBN-10 / ASIN: 0387469141
ISBN-13 / EAN: 9780387469140
Binding: Paperback
Book Description:
The Laboratory Manual is intended to accompany the Textbook to permit teaching radioanalytical chemistry to seniors and graduate students in a program that will train radiochemists, who are badly needed at this time. The manual will be used in conjunction with the textbook to teach a 3-hour lecture course and a 6-hour laboratory. The experiments address a range of practical aspects in the radiochemistry laboratory: use of laboratory and radiation detection equipment, performing specific analyses for radio-iodine, radio-strontium, uranium, and plutonium, and developing the skill of selecting and testing new procedures.
Approaches the subject from the perspective of a chromatographer who needs to know enough theory to make the best use of a chosen technique. Emphasizes the actual application of the methods--not just the theories on which they are based. This edition features a number of advances in the field since publication of the first volume. These include new chapters on high resolution gas chromatography (GC), GC detectors and classification of GC. Self-assessment questions ensure full understanding of the concepts.
Charge Migration in DNA: Perspectives from Physics, Chemistry, and Biology
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Tapash Chakraborty, "Charge Migration in DNA: Perspectives from Physics, Chemistry, and Biology (NanoScience and Technology)"
Springer; 1 edition (September 14, 2007) | ISBN: 3540724931 | 288 pages | PDF | 6,7 Mb
Charge migration through DNA has been the focus of considerable interest in recent years. A deeper understanding of the nature of charge transfer and transport along the double helix is important in fields as diverse as physics, chemistry and nanotechnology. It has also important implications in biology, in particular in DNA damage and repair. This book presents contributions from an international team of researchers active in this field. It contains a wide range of topics that includes the mathematical background of the quantum processes involved, the role of charge transfer in DNA radiation damage, a new approach to DNA sequencing, DNA photonics, and many others. This book should be of value to researchers in condensed matter physics, chemical physics, physical chemistry, and nanoscale sciences.
Handbook of Chemical and Biological Warfare Agents
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D. Hank Ellison,«Handbook of Chemical and Biological Warfare Agents»
CRC | ISBN: 0849328039 | PDF | 1,73 Mb | 528 Pages | 1999 Year
With terrorist groups expanding their weapons of destruction beyond bombs and bullets, chemical and biological warfare agents aren't merely limited to the battlefield anymore. In some cases, they are now being used on a new front: major metropolitan cities. And in the Handbook of Chemical and Biological Warfare Agents, emergency response personnel-from HazMat and Police SWAT teams to Explosive Ordinance Disposal units-will find a myriad of information on how to deal with such incidents involving dangerous chemical and biological agents.The 504-page book is formatted into a series of indices developed to facilitate rapid access to key information on chemical, biological and toxin agents, with each index cross-referenced to all others. The wealth of data not only include the physical appearance, odor, signs and symptoms of dangerous materials such as nerve agents and vesicants, but the detection and removal of such agents and the treatment of victims.
Agent Detector Characteristics
Personal Protective Equipment
Sample Collection
Summary of US Military Chemical Munition Markings
International and Domestic Lists of Agents
Glossary
References
This tutorial volume covers the basic and advanced aspects of organometallic chemistry of all metals and related catalysis topics. It treats historical background, concepts (including structures of mono- and polymetallic complexes), molecular orbitals, reactivity, implications in biology and applications to organic synthesis and catalysis. The catalysis section includes the challenging activation and functionalization of the main classes of hydrocarbons and the industrially crucial heterogeneous catalysis. Chapter-end summaries and exercises support self- and group study, with solutions included at the end of the book. 500 selected references complement the text for further reading. Chapter-length treatment of green chemistry, plus many recent international research results, round out this highly accessible textbook. Organometallic Chemistry and Catalysis can profitably be read by beginners such as undergraduate and graduate students, as well as engineers, researchers and molecular scientists from academy and industry.
Publisher: Elsevier Science
Number Of Pages: 7200
Publication Date: 2006-12-15
ISBN-10 / ASIN: 0080445136
ISBN-13 / EAN: 9780080445137
Binding: Hardcover
Book Description:
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.
Also available online via ScienceDirect (2006) featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com.
* Comprehensively reviews - the strategies, technologies, principles and applications of modern medicinal chemistry
* Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets
* Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
Product Details
»Book Publisher: Wiley-Interscience (08 April, 2003)
»ISBN: 0471287709
»Book author: Paras N. Prasad
»Amazon Rating: 3.5
Book Description:
Paras Prasad’s text provides a basic knowledge of a broad range of topics so that individuals in all disciplines can rapidly acquire the minimal necessary background for research and development in biophotonics. Introduction to Biophotonics serves as both a textbook for education and training as well as a reference book that aids research and development of those areas integrating light, photonics, and biological systems. Each chapter contains a topic introduction, a review of key data, and description of future directions for technical innovation. Introduction to Biophotonics covers the basic principles of
Optics
Optical spectroscopy
Microscopy
Each section also includes illustrated examples and review questions to test and advance the reader’s knowledge. Sections on biosensors and chemosensors, important tools for combating biological and chemical terrorism, will be of particular interest to professionals in toxicology and other environmental disciplines. Introduction to Biophotonics proves a valuable reference for graduate students and researchers in engineering, chemistry, and the life sciences.
PDF 8.5 Mb with bookmarks and page links in Contents & Index ; RAR 7.1 Mb
pass: tFINTOBIO.rar
Book Description:
This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields.
The volume provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances.
By F.D. King, G. Lawton
Publisher: Elsevier Science
Number Of Pages: 302
Publication Date: 2005-06-10
ISBN-10 / ASIN: 0444515720
ISBN-13 / EAN: 9780444515728
Binding: Hardcover
Book Description:
The Progress in Medicinal Chemistry series spans a wide range of topics of interest to the drug discovery community. This particular volume touches upon the following:
* The Herg ion channel
* Fluorescence-based high throughput assay
* Aprepitant and neurokinin receptors
* Muscarinic receptor targets
* Gene activation pathways
* Malaria and antimalarial drugs
* HIV virus mutation and new therapeutics
Progress in Medicinal Chemistry is available online on ScienceDirect full-text online of volumes 41 onwards.
Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elseviers extensive researcher network.
For more information about the Elsevier Book Series on ScienceDirect Program, please visit:
http://www.info.sciencedirect.com/bookseries/
*Presents the latest research in the field of drug discovery
*Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry
*Available as an online resource via ScienceDirect
By F.D. King, G. Lawton
Publisher: Elsevier Science
Number Of Pages: 232
Publication Date: 2007-04-13
ISBN-10 / ASIN: 0444528083
ISBN-13 / EAN: 9780444528087
Binding: Hardcover
Book Description:
The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a quality lead, where these quality leads come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.
*Presents the latest research in the field of drug discovery
*Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry
*Available as an online resource via ScienceDirect